System reliability and safety are crucial fields that have received increasing attention in recent years as technology becomes more integrated into our daily lives. The development and integration of complex systems into various applications have made it essential to ensure their reliability and safety to prevent potential disasters. Various techniques and methodologies have been developed to assess and improve system reliability and safety, such as fault diagnosis, fault-tolerant control, risk analysis, and safety management. The International Conference on System Reliability and Safety (ICSRS) is an annual event that focuses on this important theme. ICSRS has been held in several major cities including Rome, Paris, Milan, Barcelona, and Venice.