The 7th Biennial Conference of the Southern African HIV Clinicians Society (SAHCS), focusing on "Innovation to Impact: People-Centred Advances in HIV" is scheduled to be held from 20 to 22 August 2025, at Century City Conference Centre in Cape Town. The conference will be a catalyst for change, offering a dynamic forum for the latest scientific and clinical research in HIV. Our agenda includes: • Original research presentations through engaging oral and poster sessions. • CPD-accredited skills-building workshops for practical, frontline expertise. • Up to 5 plenary sessions led by global and regional thought leaders, tackling the most pressing and controversial issues in HIV management today. During SAHCS Conference 2025, we will present groundbreaking data, commemorate our shared accomplishments, explore scientific progress, and influence the future with essential interventions spanning biomedical, psychosocial, and policy realms. Our objective is to significantly reduce new HIV infections, decrease mortality from advanced HIV disease, attain sustained viral suppression, and play a decisive role in ending the AIDS epidemic by 2030.