Since founded in 2010, the International Conference on Distance Learning and Education (ICDLE) has been successfully held for 15 editions in Spain, Japan, Singapore and other countries. It was held at Nanyang Technological University, University of Barcelona, Tokyo Institute of Technology and other world-renowned universities. The 16th International Conference on Distance Learning and Education (ICDLE 2025) will be held in Barcelona, Spain during September 18-21, 2025. ICDLE 2025 will continue providing participants with an excellent international academic platform for researchers and practitioners in the field of distance learning and education to share the development results of the most cutting-edge fields; it will also be committed to providing face-to-face for representatives from different fields. To exchange new ideas and application experience, establish business or research relationships, and find opportunities for future international partners.